Wilkie Creek is a tributary of the Condamine River in the Macalister district.
A newspaper report from 1884 claimed that "in regard to Wilkie's Creek, it is without exception the finest water supply in this part of the country. It comprises a series or chain of holes, some of which are three miles in length and run as deep as 40ft. These holes withstood the heavy drought of 1876 and 1877".